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2011年美国AHA扩大脑梗死静脉溶栓治疗指南

发布时间:2014-05-19 10:34 类别:神经系统疾病 标签:III II trial enhancing 来源:丁香园

The Stroke Treatment Academic Industry Roundtable (STAIR) meetings bring together academic physicians, industry representatives, and regulators to discuss ways to enhance the development of acute and restorative stroke therapies. The first 6 STAIR meetings produced recommendations for the preclinical evaluation of stroke therapies, Phase II and Phase III trial design, enhancing trial implementation and completion, novel approaches for measuring outcome, and regulatory considerations. Despite major advances in the understanding of the pathophysiology of brain ischemia
and considerable investment in therapeutic trials, currently only a small fraction of patients with ischemic stroke receive acute treatment. The goals of STAIR VII were to propose strategies to maximize the use of intravenous (IV) thrombolytics and to suggest research priorities for the assessment of mechanical devices and neuroprotective therapies. This report is based on expert opinion distilled from discussions and workshops at the STAIR VII meeting held on September 11 and 12, 2010, in Washington, DC.